<\/span><\/h2>\r\n\r\n\r\n\r\nThe primary and major cause of haemophilia is the mutation of the genes that are responsible for controlling and regulating clotting factors. In order for blood to clot, the blood requires the clotting factors [proteins] to enable the clotting process to continue.\u00a0<\/p>\r\n\r\n\r\n\r\n
In the case of haemophilia A and B, about 2\/3rd of the mutation comes from either of the parents. The remaining fraction can come as a rather spontaneous mutation, sometimes in people who may have no family history of haemophilia whatsoever.\u00a0<\/p>\r\n\r\n\r\n\r\n
1. Haemophilia Type A and B Causes<\/strong><\/p>\r\n\r\n\r\n\r\nAs mentioned before, most types of A and B haemophilia come from parents, as a result of a recessive mutation on the X chromosome. Biological males have one X and Y chromosome, while females have two X chromosomes to complete the cycle.\u00a0<\/p>\r\n\r\n\r\n\r\n
Following this chromosome count and order, it is unlikely that biological females will inherit the disorder, as they will almost always have one non-mutated X chromosome at the least. However, they may become ‘carriers’ if they somehow acquire one copy of the mutated X chromosome.<\/p>\r\n\r\n\r\n\r\n
A carrier is a person who does not show any signs or symptoms of the particular condition in question but they can still pass on the condition to their children. For example, biological males can inherit haemophilia if their mother is a carrier and they get one copy of the mutated X chromosome from their mothers.\u00a0<\/p>\r\n\r\n\r\n\r\n
2. Haemophilia Type C Causes<\/strong><\/p>\r\n\r\n\r\n\r\nLike both type A and B, the type C condition of haemophilia can be the result of inheriting a recessive gene<\/a>. However, it has been listed separately from type A and B because type C has been known to affect both biological males and females equally.\u00a0<\/p>\r\n\r\n\r\n\r\n<\/span>Conclusion<\/strong><\/span><\/h2>\r\n\r\n\r\n\r\nWith treatment, the symptoms of haemophilia can be prevented or the condition may be further improved, however, there is currently no cure for haemophilia. If you or someone you know has been diagnosed, getting regular check-ups and treatment will help a great deal to ensure that your blood may clot normally. This World Haemophilia Day, make sure you create awareness around you about all the aspects of this disorder discussed above.<\/p>\r\n\r\n\r\n