{"id":46540,"date":"2023-12-13T16:00:00","date_gmt":"2023-12-13T10:30:00","guid":{"rendered":"https:\/\/connect.healthkart.com\/?p=46540"},"modified":"2026-01-28T12:34:10","modified_gmt":"2026-01-28T07:04:10","slug":"acanthosis-nigricans","status":"publish","type":"post","link":"https:\/\/www.healthkart.com\/connect\/acanthosis-nigricans\/","title":{"rendered":"Acanthosis Nigricans: Addressing the Common Skin Issue"},"content":{"rendered":"\r\n<p>Acanthosis Nigricans is a skin issue that occurs normally in skin folds. It causes dark, thick, and velvety skin in the affected areas, which is normally the armpits, neck, and groin. The affected areas also are itchy and have a distinct odour. Acanthosis Nigricans can be a warning sign of serious health conditions like prediabetes. The treatment process involves identifying the root cause and suggesting appropriate medication. Treating the cause will restore the normal colour of the skin.<\/p>\r\n\r\n\r\n\r\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_81 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.healthkart.com\/connect\/acanthosis-nigricans\/#Acanthosis_Nigricans_Causes\" >Acanthosis Nigricans Causes<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.healthkart.com\/connect\/acanthosis-nigricans\/#1_Medications\" >1. Medications<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.healthkart.com\/connect\/acanthosis-nigricans\/#2_Excess_Insulin_in_the_Bloodstream\" >2. Excess Insulin in the Bloodstream<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.healthkart.com\/connect\/acanthosis-nigricans\/#Other_Acanthosis_Nigricans_Causes\" >Other Acanthosis Nigricans Causes<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.healthkart.com\/connect\/acanthosis-nigricans\/#Diagnosis_of_Acanthosis_Nigricans\" >Diagnosis of Acanthosis Nigricans<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.healthkart.com\/connect\/acanthosis-nigricans\/#Acanthosis_Nigricans_Treatment_Options\" >Acanthosis Nigricans Treatment Options<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.healthkart.com\/connect\/acanthosis-nigricans\/#Conclusion\" >Conclusion<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Acanthosis_Nigricans_Causes\"><\/span><strong>Acanthosis Nigricans Causes<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\r\n\r\n\r\n\r\n<p>The abnormal growth of skin cells in the epidermis results in Acanthosis Nigricans. This growth normally happens when higher levels of insulin are found in the bloodstream. In very rare cases, the unusual reproduction of skin cells could also be due to medications, other medical conditions, or cancer.\u00a0<\/p>\r\n\r\n\r\n\r\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1_Medications\"><\/span><strong>1. Medications<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\r\n\r\n\r\n\r\n<p>Doses beyond the recommended level of some medications can trigger acanthosis nigricans. The medications are:<\/p>\r\n\r\n\r\n\r\n<ul class=\"wp-block-list\">\r\n<li>Birth control pills<\/li>\r\n\r\n\r\n\r\n<li>Supplementary insulin injection<\/li>\r\n\r\n\r\n\r\n<li>Nicotinic acid<\/li>\r\n\r\n\r\n\r\n<li>Certain bodybuilding supplements<\/li>\r\n\r\n\r\n\r\n<li>Oestrogen<\/li>\r\n\r\n\r\n\r\n<li>Protease inhibitors<\/li>\r\n<\/ul>\r\n\r\n\r\n\r\n<p>These medications disrupt the insulin levels in the body. Once the medications are stopped, the skin attains its normal colour.<\/p>\r\n\r\n\r\n\r\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"2_Excess_Insulin_in_the_Bloodstream\"><\/span><strong>2. Excess Insulin in the Bloodstream<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\r\n\r\n\r\n\r\n<p>When there is excess insulin in your bloodstream, the skin cells in the epidermis reproduce abnormally, causing acanthosis nigricans. This happens when your body develops resistance to insulin. The food you eat is converted into a sugar called glucose by your body. Insulin is necessary for the cells to use glucose for energy. Insulin should allow glucose to enter your cells for them to use glucose for energy. A part of the glucose is used for energy while your body stores the rest of it.\u00a0<\/p>\r\n\r\n\r\n\r\n<p>The body develops resistance to insulin if you are overweight. Though the body produces insulin, it cannot be used efficiently. This creates glucose buildup, which can result in excess glucose as well as insulin in your bloodstream. Excess insulin in the bloodstream leads to the rapid growth of skin cells. Excess melanin creates a patch that is darker than the skin surrounding it. The presence of these dark patches is an indicator that you may be prone to diabetes.<\/p>\r\n\r\n\r\n\r\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Other_Acanthosis_Nigricans_Causes\"><\/span><strong>Other Acanthosis Nigricans Causes<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\r\n\r\n\r\n\r\n<p>The other potential Acanthosis Nigricans causes are:<\/p>\r\n\r\n\r\n\r\n<ul class=\"wp-block-list\">\r\n<li>Genetics<\/li>\r\n\r\n\r\n\r\n<li>Autoimmune disorders like Hashimotoi\u2019s Thyroiditis or Sjogren\u2019s Disease<\/li>\r\n\r\n\r\n\r\n<li>Deficiency in thyroid hormones<\/li>\r\n\r\n\r\n\r\n<li>Gastric adenocarcinoma or stomach cancer<\/li>\r\n\r\n\r\n\r\n<li>Pituitary gland disorder<\/li>\r\n\r\n\r\n\r\n<li>High doses of niacin<\/li>\r\n<\/ul>\r\n\r\n\r\n\r\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Diagnosis_of_Acanthosis_Nigricans\"><\/span><strong>Diagnosis of Acanthosis Nigricans<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\r\n\r\n\r\n\r\n<p>Acanthosis Nigricans is usually detected during a skin examination. However, your doctor may want to identify the underlying causes like insulin resistance or diabetes and may suggest the following:<\/p>\r\n\r\n\r\n\r\n<ul class=\"wp-block-list\">\r\n<li>Blood glucose test or fasting insulin tests<\/li>\r\n\r\n\r\n\r\n<li>May review your medications to check if they are triggers. You should inform your doctor about any vitamins or bodybuilding supplements you are using besides prescription medicines for proper evaluation<\/li>\r\n\r\n\r\n\r\n<li>Sometimes, a skin biopsy may be suggested to rule out other probable causes<\/li>\r\n<\/ul>\r\n\r\n\r\n\r\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Acanthosis_Nigricans_Treatment_Options\"><\/span><strong>Acanthosis Nigricans Treatment Options<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\r\n\r\n\r\n\r\n<p>There is no specific Acanthosis Nigricans treatment as it is not a disease but a warning sign for any other probable medical condition like diabetes. Diagnosing the underlying cause and treating the same will work as a treatment method for this condition as well.<\/p>\r\n\r\n\r\n\r\n<p>If being overweight is causing acanthosis nigricans, then regular exercise and diet to maintain a healthy weight will be the treatment method. Also, medications will be prescribed to manage blood sugar levels. If the condition is due to any of the medications or supplements you are using, your doctor may suggest discontinuing them or may prescribe alternatives. When the cause is identified, and appropriate treatment is given, the dark patches will eventually fade away.<\/p>\r\n\r\n\r\n\r\n<p>For individuals who are concerned about the appearance of dark patches, cosmetic treatments will be suggested. It may include using skin lighteners, laser therapy, or oral acne medications. However, these treatments will only work on the appearance and will not help cure the condition.\u00a0<\/p>\r\n\r\n\r\n\r\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Conclusion\"><\/span><strong>Conclusion<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\r\n\r\n\r\n\r\n<p>Acanthosis Nigricans is not a disease. It is a skin condition that is triggered by excess insulin in your bloodstream. This could be due to insulin resistance developed due to obesity. When insulin produced by your body is not effectively utilised by cells to take glucose to derive energy, there will be a buildup of glucose in your bloodstream. This will result in the rapid reproduction of skin cells that cause dark, velvety patches in skin folds.\u00a0<\/p>\r\n\r\n\r\n\r\n<p>The development of Acanthosis Nigricans can be an indicator of enhanced risk of diabetes. Early recognition of the underlying cause and treatment is crucial to prevent progression into serious health issues.\u00a0<\/p>\r\n","protected":false},"excerpt":{"rendered":"<p>Acanthosis Nigricans is a skin issue that occurs normally in skin folds. It causes dark, thick, and velvety skin in the affected areas, which is normally the armpits, neck, and groin. The affected areas also are itchy and have a distinct odour. Acanthosis Nigricans can be a warning sign of serious health conditions like prediabetes. [&hellip;]<\/p>\n","protected":false},"author":192,"featured_media":46545,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[1,1024],"tags":[],"secondary_tag":[],"class_list":{"0":"post-46540","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-chronic-conditions","8":"category-english","9":"entry"},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Acanthosis Nigricans Explained: Causes and More - HealthKart<\/title>\n<meta name=\"description\" content=\"Acanthosis Nigricans is a skin condition that may be common in people with diabetes or prediabetes. 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